Πλοήγηση ανά Θέμα "genetic marker"
Αποτελέσματα 1-20 από 22
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Bone mineral density and genetic markers involved in three connected pathways (focal adhesion, actin cytoskeleton regulation and cell cycle): The CUMAGAS-BMD information system
(2011)The focal adhesion, the actin cytoskeleton and cell-cycle are connected pathways and their genes are implicated in the pathogenesis of low BMD. Data from 211 studies that investigated the association between BMD and gene ... -
Changes of serum sclerostin and Dickkopf-1 levels during the menstrual cycle. A pilot study
(2016)Studies in postmenopausal women have identified sclerostin as a strong candidate for mediating estrogen effects on the skeleton. The effects of estradiol on sclerostin and Dickkopf-1 in younger women remain unclear. The ... -
Emerging molecular networks common in ionizing radiation, immune and inflammatory responses by employing bioinformatics approaches
(2015)Efficient radiation therapy is characterized by enhanced tumor cell killing involving the activation of the immune system (tumor immunogenicity) but at the same time minimizing chronic inflammation and radiation adverse ... -
Epidemiological investigation of Legionella pneumophila serogroup 2 to 14 isolates from water samples by amplified fragment length polymorphism and sequence-based typing and detection of virulence traits
(2016)The aim of this study is to explore the dispersion, clonality, and virulence of Legionella pneumophila serogroups 2 to 14 in the Greek environment. Eighty L. pneumophila serogroup 2 to 14 strains isolated from water ... -
Evaluation of 12 GWAS-drawn SNPs as biomarkers of rheumatoid arthritis response to TNF inhibitors. A potential SNP association with response to etanercept
(2019)Research in rheumatoid arthritis (RA) is increasingly focused on the discovery of biomarkers that could enable personalized treatments. The genetic biomarkers associated with the response to TNF inhibitors (TNFi) are among ... -
FCGR3A-V158F polymorphism is a disease-specific pharmacogenetic marker for the treatment of psoriasis with Fc-containing TNFα inhibitors
(2017)Psoriasis is a multifactorial skin disease affecting ∼2% of world's population, causing a dramatic decrease in patients' quality of life and a significant increase in health-care expenses. Biological agents such as the ... -
Genetic sexing strains for the population suppression of the mosquito vector Aedes aegypti: Aedes aegypti genetic sexing strains
(2021)Aedes aegypti is the primary vector of arthropod-borne viruses including dengue, chikungunya and Zika. Vector population control methods are reviving to impede disease transmission. An efficient sex separation for male-only ... -
Genetic variation in Wnt/β-catenin and ER signalling pathways in female and male elite dancers and its associations with low bone mineral density: a cross-section and longitudinal study
(2018)Summary: The association of genetic polymorphisms with low bone mineral density in elite athletes have not been considered previously. The present study found that bone mass phenotypes in elite and pre-elite dancers are ... -
Irradiation induced inversions suppress recombination between the M locus and morphological markers in Aedes aegypti
(2020)Background: Aedes aegypti is the primary vector of arthropod-borne viruses and one of the most widespread and invasive mosquito species. Due to the lack of efficient specific drugs or vaccination strategies, vector population ... -
Making IVF more effective through the evolution of prediction models: is prognosis the missing piece of the puzzle?
(2018)Assisted reproductive technology has evolved tremendously since the emergence of in vitro fertilization (IVF). In the course of the recent decade, there have been significant efforts in order to minimize multiple gestations, ... -
Molecular diagnostic testing for primary biliary cholangitis
(2016)Introduction: A reliable liver autoimmune serology for the diagnosis of primary biliary cholangitis (PBC) is of particular importance. Recognition of patients at early stages and prompt treatment initiation may alter the ... -
Morphology and Genetic Structure Profile of Farmed Snails Cornu aspersum aspersum and Cornu aspersum maximum in Greece
(2022)The subspecies of the species Cornu aspersum, C. a. aspersum, and C. a. maximum are the dominant farmed species in Greece. The morphological and molecular polymorphism of the two aforementioned subspecies has not been ... -
Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease
(2008)Susceptibility to sporadic Parkinson's diseases (PD) is thought to be influence by both genetic and environmental factors and thier interaction with each other. Statistical models including multiples variants in axon ... -
Old residents and new arrivals of Rhagoletis species in Europe
(2019)The genus Rhagoletis (Diptera: Tephritidae) comprises more than 65 species distributed throughout Europe, Asia and America, including many species of high economic importance. Currently, there are three Rhagoletis species ... -
Patient with prostatic adenocarcinoma with plasmacytoid features and an aberrant immunohistochemical phenotype diagnosed by biopsy and a mini-review of plasmacytoid features in the genitourinary system: A case report
(2022)Prostate cancer is one of the most commonly diagnosed malignancies in men. Most of these tumors are adenocarcinomas. Plasmacytoid is a rare variant of adenocarcinoma described by previous studies in the genitourinary system ... -
Pharmacogenetics and psoriasis: Is targeted treatment a possibility?
(2017)[No abstract available] -
Population genetics of cape and brown hares (Lepus capensis and L. europaeus): A test of Petter's hypothesis of conspecificity
(2008)Phylogenetic relationships and systematics of hares and jackrabbits (genus Lepus, Lagomorpha) are notoriously difficult. One intriguing issue is the relationship between cape hares (Lepus capensis L., 1758) and brown hares ... -
Replicating a GWAS: two novel candidate markers for oligospermia in Greek population
(2021)Genome-wide association studies have paved the way for the discovery of new markers regarding many diseases, including male infertility. A previous study on Caucasians highlighted 172 polymorphisms for their putative ... -
Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis
(2016)Genetic biomarkers could be useful for orienting treatment of patients with rheumatoid arthritis (RA), but none has been convincingly validated yet. Putative biomarkers include 14 single nucleotide polymorphisms that have ... -
The role of genetic polymorphisms of the Renin-Angiotensin System in renal diseases: A meta-analysis
(2014)Renal failure has a complex phenotype resulting from an underlying kidney disease as well as environmental and genetic factors. In the present study we performed a systematic review and meta-analyses to evaluate the ...